The object dialog box will appear select create from file. If an overdose occurs, it should be treated symptomatically with laboratory monitoring and supportive measures should be instituted as required. Fluvastatin is an expensive drug used with a proper diet to lower high cholesterol and triglycerides fats in the blood. Easy to read fda package insert, drug facts, dosage and administration, and adverse effects for lescol fluvastatin skip to. Lipitor can pass into your breast milk and may harm your baby. Here are two steps to insert pdf into word document as an object. Fluvastatin capsules fda prescribing information, side. See the end of this leaflet for a complete list of ingredients in lipitor. Easy to read fda package insert, drug facts, dosage and administration, and adverse effects for pravachol pravastatin. Graham mayor microsoft word mvp 20022019 for more word tips and downloads visit my web site. Fluvastatin is also prescribed to slow the progression of coronary heart disease. It belongs to a class of drugs called hmgcoa reductase inhibitors, commonly called statins.
Fluvastatin is also used to lower the risk of heart. In those with heart disease, it can also reduce the chances of needing open heart surgery, among other things. Dosing ranges from 20 mg 80 mg, taken orally every day. When you click on object, youll get a dialog box, and here you will want to click on the create from file tab. This inhibition reduces cholesterol concentration in hepatic cells, which in turn increases synthesis. For outlook, click inside of the body of an item, such as an email message or calendar event. A statin drug, c24h26fno4, that blocks the bodys synthesis of cholesterol and is used in the form of its sodium salt to lower cholesterol especially ldl levels and to reduce the risk of heart attack and stroke in individuals with elevated risk.
If an overdose occurs, it should be treated symptomatically with laboratory monitoring and. Fluvastatin lescol side effects, dosage, interactions drugs. Mar 03, 2017 lescol fluvastatin sodium capsules 20 mg, 40 mg. Place your cursor by clicking on the area where you wish to insert the pdf document. The extendedrelease form is a longacting version of fluvastatin. Lescol fluvastatin lipitor atorvastatin livalo pitavastatin mevacor lovastatin pravachol pravastatin zocor. As this emedtv page explains, fluvastatin is used to treat high cholesterol and high triglycerides. While working on your document, click insert object.
If you take more fluvastatin capsules than you should if you have accidentally taken too much fluvastatin, talk to your doctor straight away. Hmg coa reductase inhibitors statins vha pharmacy benefit management strategic healthcare group and the medical advisory panel white zone available generically. Read the patient information every time you or a family member gets lescol or lescol xl. Fluvastatin sodium can pass into your breast milk and may harm your baby. These highlights do not include all the information needed to use losartan potassium and hydrochlorothiazide. Reduce elevated tc, ldlc, apo b, and tg, and to increase hdlc in adult patients with primary hypercholesterolemia and mixed dyslipidemia reduce elevated tc, ldlc, and apo b levels in boys and postmenarchal girls, 10 to 16 years of age, with heterozygous familial. If you are taking fluvastatin twice per day, take one capsule in the morning and one in the evening or at bedtime.
Fluvastatin definition at, a free online dictionary with pronunciation, synonyms and translation. Pronunciation of fluvastatin with 1 audio pronunciation, 4 synonyms, 7 translations and more for fluvastatin. Highlights of prescribing information these highlights do not. Cardiovascular risk associated with rapid infusion rates see full prescribing information for complete boxed warning the rate of intravenous cerebyx administration should not exceed 150 mg phenytoin sodium equivalents pe per minute in adults and 2 mg pekgmin or 150 mg pemin, whichever is slower in pediatric patients because of the risk of severe hypotension and cardiac. Here are the steps to inserting a pdf file into a word document. Fluvastatin medical definition merriamwebster medical. In this article, when we refer to lescol, we are talking about both lescol and lescol xl, unless otherwise specified. Fluvastatin is the generic form of the brandname drug lescol, which is used to treat high cholesterol and help prevent certain heart problems. Reduce the risk of mi and stroke in adult patients with type 2 diabetes without chd, but with multiple risk factors. Dailymed fluvastatin sodium er fluvastatin sodium tablet. Fluvastatin, the first fully synthetic hmgcoa reductase inhibitor, has been shown to reduce cholesterol in patients with hyperlipidaemia, to prevent subsequent coronary events in patients with established coronary heart disease, and to alter endothelial function and plaque stability in animal models. Cardiovascular risk associated with rapid infusion rates see full prescribing information for complete boxed warning the rate of intravenous cerebyx administration should not exceed 150 mg phenytoin sodium equivalents pe per minute in adults and 2 mg pekgmin or 150 mg pemin, whichever is slower in pediatric patients because of the risk of severe hypotension and.
Fluvastatin is a synthetic lipidlowering agent with antilipidemic and potential antineoplastic properties. Fluvastatin sodium definition of fluvastatin sodium by. Statins reduce cholesterol by inhibiting an enzyme in the liver hmgcoa reductase that is necessary for the production of cholesterol. Reduce the risk of mi, stroke, revascularization procedures, and angina in adult patients without chd, but with multiple risk factors. Fluvastatin is used together with diet to lower blood levels of bad cholesterol lowdensity lipoprotein, or ldl, to increase levels of good cholesterol highdensity lipoprotein, or hdl, and to lower triglycerides a type of fat in the blood fluvastatin is used to slow the buildup of plaque fatty deposits in your blood vessels. This supplemental new drug application proposes changes in the format of the pravachol package insert in response to the physicians labeling rule plr. Lipitor is an hmgcoa reductase inhibitor indicated as an adjunct therapy to diet to. Under object type, select adobe acrobat document and click ok. It is not covered by most medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost. Other statins include lovastatin, atorvastatin, simvastatin, and rosuvastatin.
Clinical pharmacokinetics of fluvastatin springerlink. Fluvastatin competitively inhibits hepatic 3hydroxy3methylglutaryl coenzyme a reductase, which catalyzes the conversion of hmgcoa to mevalonate, a key step in cholesterol synthesis. Fluvastatin is cleared by the liver, with less than 6% of the administered dose excreted into the urine. Fluvastatin is used along with a proper diet to help lower bad cholesterol and fats such as ldl, triglycerides and raise good cholesterol hdl in the blood. Fluvastatin lescol side effects, dosage, interactions. Antihyperlipidemic pregnancy risk category x action competitively inhibits hmgcoa reductase, an enzyme needed to synthesize cholesterol. This emedtv segment offers an indepth look at this drug and its uses, possible side effects, and dosages, with links to additional information. Fluvastatin is relatively hydrophilic, compared with the semisynthetic hmgcoa reductase. Oct 31, 2012 fluvastatin sodium is a white to pale yellow, hygroscopic powder soluble in water, ethanol and methanol. Sustainedrelease doses are taken at the full 80 mg, taken orally every day. Highlights of prescribing information these highlights do. Fluvastatin definition of fluvastatin by medical dictionary.
Easy to read fda package insert, drug facts, dosage and administration, and adverse effects for lescol fluvastatin. Lipitor dosing has not been established in children under 10 years of age. To date, there has been limited experience with overdosage of fluvastatin. Embed pdf in word embed a pdf document into microsoft word. Click insert to insert the images into the word document. The content on this site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. Fluvastatin capsules can be taken with or without meals. Fluvastatin has only been investigated in children of 9 years and older with heterozygous familial hypercholesterolaemia. This medicine may help prevent medical problems, like atherosclerosis hardening of the arteries, that are caused by fats clogging the blood vessels. Reduce the risk of nonfatal mi, fatal and nonfatal. Reduce elevated tc, ldlc, apo b, and tg, and to increase hdlc in adult patients with primary hypercholesterolemia and mixed dyslipidemia reduce elevated tc, ldlc, and apo b levels in boys and postmenarchal girls. Fda package insert for fluvastatin contains no information regarding iv compatibility. You must read and follow all instructions before using lescol or lescol xl.
Generic fluvastatin is covered by some medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Fluvastatin definition of fluvastatin by the free dictionary. Human hepatocellular carcinoma cell hcc studies indicate that fluvastatin induces g2m phase arrest. Fluvastatin sodium capsules, usp fluvastatin sodium extendedrelease tablets, usp is an hmgcoa reductase inhibitor statin indicated as an adjunctive therapy to diet to. Over the dose range of 10 to 80 mgday total cholesterol was reduced by 10. Fluvastatin is antilipemic and is used to reduce plasma cholesterol levels and prevent.
However, this will only insert the text without the original formatting or graphics if any from the pdf file, so it wont look. Fluvastatin er is an expensive drug used together with a proper diet to lower high cholesterol and triglycerides fats in the blood. In the text group click the dropdown arrow for object and select object. The active ingredient in fluvastatin capsules is fluvastatin.
In this article, when we refer to fluvastatin, we are referring to both fluvastatin sodium and fluvastatin. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease. Fluvastatin is a medication commonly used for the treatment of high cholesterol and high triglycerides. Food and drug administration, center for drug evaluation and research. You can also import a portion of text from the pdf file using the insert object tool, and drop it into the word document. Lescol xl fluvastatin sodium extendedrelease tablets 80 mg.
Fluvastatin is used together with a proper diet to lower high cholesterol and triglycerides fats in the blood. For patients requiring 80mg per day, doses should be divided into two 40 mg doses taken orally, every 12 hours. Microsoft word program can help you insert pdf into word doc directly, however it is only inserted as an object that cannot be edited. This will insert the pdf first page only as objects cannot span pages just as in earlier versions, without converting the pdf. Fluvastatin is in a class of medications called hmgcoa reductase inhibitors statins. Jul 22, 2019 fluvastatin is secreted into the breast milk of animals and because hmgcoa reductase inhibitors have the potential to cause serious adverse reactions in nursing infants, women who require treatment with fluvastatin capsules should be advised not to breastfeed their infants see use in specific populations. Patients start fluvastatin at 20 mg 40 mg, taken orally every night at bedtime. The pharmacokinetics of fluvastatin remain unchanged in patients with mild to severe renal. Fluvastatin capsules are an hmgcoa reductase inhibitor statin indicated as an adjunctive therapy to diet to.
Open the word document and select insert on the ribbon. For people with heart disease, it can also decrease the chances of requiring a heart procedure such as angioplasty or open heart surgery and reduce the rate of cholesterol buildup on the arteries. Lescol, lescol xl is a statin drug prescribed to reduce total blood cholesterol and triglyceride levels along with diet. In the presence of fluvastatin, hcc cells show a decrease of bcl2 and procaspase9 expression, and an increase in bax, cleaved caspase3, and cytochrome c. This polymorphism is proposed to reduced transport into the liver, the main site of statin metabolism and elimination, resulting in elevated plasma concentrations slco1b1 polymorphism is thought to have a lesser effect on the more hydrophilic statins eg, rosuvastatin, fluvastatin compared with more those that are more lipophilic eg. Highlights of prescribing information these highlights do not include all the information needed to use pravachol safely and effectively. Information and translations of fluvastatin in the most comprehensive dictionary definitions resource on the web. See the end of this leaflet for a complete list of ingredients in fluvastatin capsules. It works by slowing the production of cholesterol in the body to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body. Fluvastatin sodium extendedrelease tablets, usp are supplied as extendedrelease tablets containing fluvastatin sodium, equivalent to 80 mg of fluvastatin, for oral administration. Fluvastatin works by blocking the liver enzyme hmgcoa reductase, which facilitates an important step in cholesterol synthesis pharmacodynamics. It is approved, effective on the date of this letter, for use as recommended in the enclosed, agreedupon labeling text.
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